Preferred Label : Blast Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive;
NCIt synonyms : Blastic Phase CML; Blast Phase Chronic Myelogenous Leukemia; Blast Phase Chronic Granulocytic Leukemia; Blastic Phase Chronic Myelocytic Leukemia; Blast Phase CML; Blastic Phase Chronic Granulocytic Leukemia; Blast Phase Chronic Myeloid Leukemia; Blast Phase Chronic Myelocytic Leukemia; Blastic Phase Chronic Myeloid Leukemia; Blast Phase Chronic Myelogenous Leukemia, BCR::ABL1 Positive; Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Blast Phase Chronic Myeloid Leukemia, BCR::ABL1 Positive;
NCIt related terms : blastic phase chronic myelogenous leukemia; blast crisis;
NCIt definition : An advanced phase of chronic myeloid leukemia. It is characterized by: 1. the presence
of blasts in the peripheral blood or bone marrow that are at least 20% of the peripheral
blood white cells or of the nucleated cells in the bone marrow respectively, or 2.
an extramedullary proliferation of blasts, and/or 3. when there are large aggregates
and clusters of blasts in the bone marrow biopsy specimen (adapted from WHO, 2001).;
Alternative definition : NCI-GLOSS: A phase of chronic myelogenous leukemia in which 20% or more of the cells
in the blood or bone marrow are blast cells (immature blood cells). When tiredness,
fever, and an enlarged spleen occur during the blastic phase, it is called blast crisis.;
Neoplastic status : Malignant;
Codes from synonyms : CDR0000046502; CDR0000046113;
Origin ID : C9110;
UMLS CUI : C0005699;
Currated CISMeF NLP mapping
- Disease excludes normal cell origin
- Disease may have findings
- Has associated anatomic sites
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to NTBT
- concept_is_in_subset
- disease_excludes_finding
- disease_excludes_molecular_abnormality
- disease_has_abnormal_cell
- disease_has_associated_disease
- disease_has_finding
- disease_has_molecular_abnormality
- disease_has_normal_cell_origin
- disease_has_normal_tissue_origin
- disease_has_primary_anatomic_site
- disease_mapped_to_gene
- disease_may_have_associated_disease
- disease_may_have_cytogenetic_abnormality
