Preferred Label : Allogeneic Cytomegalovirus-Specific Cytotoxic T lymphocytes;
NCIt definition : A population of allogeneic cytotoxic T lymphocytes (CTLs) specifically reactive to
the herpes virus cytomegalovirus (CMV) with potential immunomodulating and antiviral
activities. Upon immunoprophylactic adoptive cell therapy infusion with allogeneic
cytomegalovirus-specific cytotoxic T lymphocytes, these CTLs may help reconstitute
CMV-specific CTL responses in CMV-infected immunocompromised hosts after allogeneic
hematopoietic stem cell transplant, thereby potentially preventing the occurrence
of CMV viral disease or reducing the amount of antiviral drug therapy.;
NCI Metathesaurus CUI : CL421481;
Origin ID : C91095;
UMLS CUI : C2984034;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
