Reteplase - CISMeF

Preferred Label : Reteplase;

NCIt synonyms : Human T-PA (Amino Acids 1-3 and 176-527);

NCIt definition : A recombinant, non-glycosylated deletion mutein of tissue plasminogen activator (tPA), a serine protease that catalyzes the cleavage of plasminogen to plasmin, with fibrinolytic activity. Upon administration, reteplase converts plasminogen to plasmin, thereby increasing plasmin enzymatic activity and resulting in degradation of the fibrin matrix of the thrombus and potential dissolution of a thrombus or embolism.;

UNII : DQA630RIE9;

CAS number : 133652-38-7;

Drug name : Retavase;

Molecule name : BM-06022; CUSA-081; CUSA 081;

Details

Origin ID

C90972;

UMLS CUI

C0256103;

See also inter- (CISMeF)
- Product containing reteplase (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing reteplase (medicinal product) [SNOMED CT concept]
- Reteplase (substance) [SNOMED CT concept]
- reteplase [ATC Code]
- reteplase [International Nonproprietary Name]
- reteplase [MeSH Supplementary Concept]
- reteplase [MeSH concept]
Validated automatic mappings to BTNT
- reteplase [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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