NCIt definition : A selective serotonin (5-HT) reuptake inhibitor (SSRI) and a 5-HT-1A receptor partial
agonist, with antidepressant and anti-anxiety activities. Vilazodone inhibits the
reuptake of serotonin from the synaptic cleft while stimulating the release of 5-HT
into the synaptic cleft. This increases the concentration of 5-HT in the synaptic
cleft and potentiates serotonergic neurotransmission in the central nervous system.;