Preferred Label : Omadacycline;
NCIt synonyms : (4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-9-{[(2,2-dimethylpropyl)amino]methyl}- 3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-
carboxamide; Amadacyclin; 2-naphthacenecarboxamide, 4,7-bis(dimethylamino)-9-(((2,2-dimethylpropyl)amino)methyl)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-,
(4s,4aS,5aR,12aS)-, 4-methylbenzenesulfonate (1:1);
NCIt definition : An aminomethylcycline and a semisynthetic tetracycline derivative, with antimicrobial
activity. Upon administration, omadacycline binds to the bacterial 30S ribosomal subunit
and inhibits bacterial protein synthesis. Omadacycline is engineered to overcome certain
tetracycline resistance mechanisms, including tetracycline-specific efflux pumps and
ribosomal protection.;
UNII : 090IP5RV8F;
InChIKey : JEECQCWWSTZDCK-IQZGDKDPSA-N;
CAS number : 389139-89-3;
Molecule name : PTK 0796;
Chemical formula : C29H40N4O7;
Origin ID : C90688;
UMLS CUI : C2983838;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- has_salt_form
- is_free_acid_or_base_form_of
