Amolimogene Bepiplasmid

Preferred Label : Amolimogene Bepiplasmid;

NCIt synonyms : Bacterially Derived DNA and Microparticles Made of Poly(D,L-lactide-co-glydolide); Amolimogene; DNA (synthetic Plasmid p3kDRalphaHPV16-18);

NCIt definition : A plasmid DNA-based vaccine consisting of small biodegradable poly(lactide-co-glicolide) polymer microparticles encapsulating plasmid-DNA vector encoding a chimeric protein comprising epitopes derived from the E6 and E7 oncoproteins of the human papillomavirus (HPV) types 16 and 18, with potential antineoplastic activity. Upon intramuscular vaccination, amolimogene bepiplasmid may elicit the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells positive for HPV-16 and -18 E6 and E7 and may result in a reduction in tumor cell growth. HPV types 16 and 18 oncoproteins E6 and E7 are most commonly involved in cervical cancer.;

UNII : 8B5KCA0GAK;

CAS number : 870524-46-2;

Molecule name : ZYC101a;

Details

Origin ID

C90592;

UMLS CUI

C2607725;

Currated CISMeF NLP mapping
- amolimogene bepiplasmid [MeSH concept]
- amolimogene bepiplasmid [MeSH Supplementary Concept]
Semantic type(s)
- Immunologic Factor [UMLS semantic type]
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- amolimogene bepiplasmid [MeSH Supplementary Concept]
- amolimogene bepiplasmid [MeSH concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Protein E6, Human Papillomavirus Type 16 [NCIt concept]
- Protein E6, Human Papillomavirus Type 18 [NCIt concept]
- Protein E7, Human Papillomavirus Type 16 [NCIt concept]
- Protein E7, Human Papillomavirus Type 18 [NCIt concept]

Keyword's position in hierarchy(ies) :

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