Preferred Label : Fluorine F-18 Fluoropaclitaxel;
NCIt synonyms : 18F-FPAC;
NCIt definition : A radiotracer containing paclitaxel labeled with the radioisotope fluorine F18 with
potential use as an imaging agent. After cellular uptake, the paclitaxel moiety of
fluorine F18 fluoropaclitaxel binds to tubulin. Upon uptake, the radioisotope moiety
may be detected using positron emission tomography (PET), thereby allowing imaging
and quantification of the biodistribution of paclitaxel. This could identify multidrug
resistant (MDR) status of tumor cells and select patients that will likely respond
to paclitaxel treatment.;
NCI Metathesaurus CUI : CL421241;
Origin ID : C90580;
UMLS CUI : C2983779;
Semantic type(s)
- concept_is_in_subset
- has_target
