NCIt definition : A humanized IgG1 monoclonal antibody directed against the epidermal growth factor-like
domain multiple 7 (EGFL7) with potential antineoplastic activity. Parsatuzumab binds
to EGFL7, thereby preventing the activities of EGFL7 on endothelial cells and inhibiting
the survival and migration of endothelial cells during angiogenesis. EGFL7, a vascular-restricted
extracellular matrix protein which is upregulated during angiogenesis and which regulates
vascular development, may be overexpressed on the cell surfaces of various solid tumor
cell types.;
UNII : 435M4HCP2M;
CAS number : 1312797-14-0; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1312797-14-0
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G-SRS /a ;
Molecule name : MEGF0444A; RG7414; RG 7414; MEGF 0444A;