Preferred Label : ALVAC-ESO-1 Vaccine;
NCIt definition : A cancer vaccine consisting of a replication-defective recombinant canarypox virus
(ALVAC) encoding the cancer-testis antigen NY-ESO-1, with potential immunostimulatory
and antineoplastic activities. Upon administration, ALVAC-ESO-1 vaccine may stimulate
the host immune system to mount a cytotoxic T lymphocyte (CTL) response against NY-ESO-1-expressing
cancer cells, which may result in the inhibition of tumor cell proliferation. NY-ESO-1,
a tumor associated antigen (TAA), is found in normal testis and on the surface of
various tumor cells.;
NCI Metathesaurus CUI : CL416242;
Origin ID : C90558;
UMLS CUI : C2983757;
Semantic type(s)
- concept_is_in_subset
