Preferred Label : Eg5 Kinesin-Related Motor Protein Inhibitor 4SC-205;
NCIt synonyms : Eg5 Kinesin Inhibitor 4SC-205;
NCIt definition : A small-molecule inhibitor of the human kinesin-related motor protein Eg5 with potential
antineoplastic activity. Eg5 kinesin-related motor protein inhibitor 4SC-205 selectively
inhibits the activity of Eg5, which may result in mitotic disruption, apoptosis and
cell death. The ATP-dependent Eg5 kinesin-related motor protein (also known as KIF11
or kinesin spindle protein-5) is a plus-end directed kinesin motor protein essential
for the regulation of spindle dynamics, including assembly and maintenance, during
mitosis.;
Molecule name : SC-205; 4SC 205; 4SC-205;
NCI Metathesaurus CUI : CL416241;
Origin ID : C90557;
UMLS CUI : C2983756;
Semantic type(s)
- concept_is_in_subset
