Preferred Label : Ruxotemitide;
NCIt definition : A peptide derived from human lactoferrin, with potential lytic and immunostimulating
activities. Upon transdermal injection directly into the tumor, ruxotemitide may bind
to the tumor cell membranes and subsequently lyse tumor cells, thereby inducing tumor
cell necrosis. In turn, presentation of the tumor antigens to the immune system may
induce systemic innate and adaptive immune responses mediated by anti-tumor natural
killer (NK) cells, cytotoxic T lymphocytes, and natural killer T (NKT) cells. This
may trigger an immune response against tumor associated antigens on tumors distant
from the primary tumor. Human lactoferrin, a 692 amino acid glycoprotein, belongs
to the transferrin family of metal-binding proteins.;
UNII : 75FBL12IZ7;
InChIKey : GGAKLYWEFZCVIT-TVEKFXMRSA-N;
CAS number : 1345407-05-7;
Drug name : Oncopore;
Molecule name : LTX-315;
NCI Metathesaurus CUI : CL416231;
Origin ID : C90547;
UMLS CUI : C5239398;
Semantic type(s)
- UMLS correspondences (same concept)
- LTX-315 [MeSH Supplementary Concept]
- concept_is_in_subset
