Preferred Label : DCR Ligand-Bearing Liposome-Encapsulated Melanoma Antigens Vaccine;
NCIt synonyms : Dendritic Cell Receptor Ligand-Bearing Liposome-Encapsulated Melanoma Antigens Vaccine;
NCIt definition : A cancer cell-based vaccine containing liposome encapsulated melanoma antigens and
an immunomodulatory factor, attached, via a metal chelator, to a dendritic cell receptor
(DCR) ligand-containing a metal-affinity tag, with potential immunomodulating and
antineoplastic activity. Upon intravenous administration of DCR ligand-bearing liposome-encapsulated
melanoma antigens vaccine, the DCR ligand moiety of this vaccine targets receptors
on dendritic cells (DCs), thereby presenting the antigens to DCs which may, in turn,
stimulate the DCs and may activate the immune system to mount a cytotoxic T lymphocyte
(CTL) response against melanoma cancer cell associated antigens.;
Drug name : Lipovaxin-MM;
NCI Metathesaurus CUI : CL416224;
Origin ID : C90543;
UMLS CUI : C2983739;
Semantic type(s)
- concept_is_in_subset
