TLR9 Agonist EMD 1201081

Preferred Label : TLR9 Agonist EMD 1201081;

NCIt synonyms : Toll-like Receptor 9 Agonist EMD 1201081;

NCIt definition : A synthetic oligonucleotide containing phosphorothioate oligodeoxynucleotide with potential immunopotentiating activity. TLR9 agonist EMD 1201081 binds to and activates the intracellular Toll-like receptor (TLR) 9 in monocytes/macrophages, plasmacytoid dendritic cells (DCs) and B cells, initiating immune signaling pathways, activating B cells and inducing T-helper cell cytokine production. TLR9 is a member of the TLR family, which plays a fundamental role in pathogen recognition and activation of innate immunity.;

Molecule name : EMD 1201081;

Details

Origin ID

C90533;

UMLS CUI

C2983728;

Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- EMD 1201081 [MeSH concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_target
- Toll-Like Receptor 9 [NCIt concept]

Keyword's position in hierarchy(ies) :

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