NCIt synonyms : Mucin 5, Subtypes A and C, Tracheobronchial/Gastric Gene; Mucin 5AC, Oligomeric Mucus/Gel-Forming wt Allele; Mucin 5A Gene; MUC5; Mucin 5, Tracheobronchial/Gastric Gene; Lewis B Blood Group Antigen Gene; TBM; leB;
NCIt definition : Human MUC5AC wild-type allele is located in the vicinity of 11p15.5 and is approximately
146 kb in length. This allele, which encodes mucin-5AC protein, is involved in the
formation of the mucosa of the respiratory and gastrointestinal tracts. This gene
is aberrantly expressed in many carcinomas and in Barrett esophagus.;
NCIt note : The MUC5AC gene may be a marker of precancerous pancreatic cysts. (Annals of Surgery.
2010; 251: 937-945.);