ADAM8 wt Allele

Preferred Label : ADAM8 wt Allele;

NCIt synonyms : CD156; MS2; Human Leukocyte Differentiation Antigen Gene; A Disintegrin and Metalloproteinase Domain 8 Gene; MGC134985; ADAM Metallopeptidase Domain 8 wt Allele;

NCIt definition : Human ADAM8 wild-type allele is located in the vicinity of 10q26.3 and is approximately 14 kb in length. This allele, which encodes disintegrin and metalloproteinase domain-containing protein 8, plays a role in the regulation of proteolysis. The gene may be involved in neurodegeneration and allergic respiratory diseases.;

NCIt note : The ADAM8 gene was shown to be essential for establishing blood flow in zebrafish embryos. (Current Biology. 2010; 20: 1110-6.);

GenBank Accession Number : D26579;

Details

Origin ID

C90315;

UMLS CUI

C2983550;

OMIM relation
- A disintegrin and metalloproteinase domain 8 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_plays_role_in_process
- Hydrolysis [NCIt concept]
- Integrin Binding [NCIt concept]
- Metal Ion Binding [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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