MYD88 wt Allele

Preferred Label : MYD88 wt Allele;

NCIt synonyms : MYD88D; Myeloid Differentiation Primary Response Gene (88); Myeloid Differentiation Primary Response Gene 88; Myeloid Differentiation Primary Response 88 wt Allele;

NCIt definition : Human MYD88 wild-type allele is located in the vicinity of 3p22 and is approximately 5 kb in length. This allele, which encodes myeloid differentiation primary response protein MyD88, plays a role in both protein-protein interactions and the regulation of the expression of proinflammatory genes. Mutation of the gene is associated with recurrent pyogenic bacterial infections.;

NCIt note : The MYD88 gene may be involved in lung tumor metastasis.;

GenBank Accession Number : U84408;

Details

Origin ID

C90095;

UMLS CUI

C2983360;

OMIM relation
- Myd88 innate immune signal transduction adaptor [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 3p22 [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- MCD Diffuse Large B-Cell Lymphoma [NCIt concept]
- Primary Vitreoretinal Non-Hodgkin Lymphoma [NCIt concept]
gene_plays_role_in_process
- Immunity [NCIt concept]
- Inflammatory Response [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]

Keyword's position in hierarchy(ies) :

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