MECR wt Allele

Preferred Label : MECR wt Allele;

NCIt synonyms : FASN2B; CGI-63; NRBF1; Mitochondrial Trans-2-Enoyl-CoA Reductase wt Allele; Nuclear Receptor Binding Factor 1 Gene; Mitochondrial 2-Enoyl Thioester Reductase Gene;

NCIt definition : Human MECR wild-type allele is located within 1p36.1-p35.1 and is approximately 38 kb in length. This allele, which encodes trans-2-enoyl-CoA reductase, mitochondrial protein, is involved in the mediation of acyl-CoA synthesis.;

NCIt note : A deletion in the MECR gene may play a role in breast cancer metastasis. (Nature. 2010; 464: 999-1005.);

GenBank Accession Number : NM_016011;

PubMed : 20393555;

Details

Origin ID

C89009;

UMLS CUI

C2982453;

OMIM relation
- Mitochondrial trans-2-enoyl-coa reductase [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_is_element_in_pathway
- Fatty Acid Elongation Pathway in Mitochondria [NCIt concept]
gene_plays_role_in_process
- Fatty Acid Metabolism [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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