CTNNA1 wt Allele

Preferred Label : CTNNA1 wt Allele;

NCIt synonyms : FLJ52416; FLJ36832; CAP102; Catenin (Cadherin-Associated Protein), Alpha 1 (102kD) Gene; Catenin, Alpha-1 Gene; Catenin Alpha 1 wt Allele; Catenin (Cadherin-Associated Protein), Alpha 1, 102kDa Gene; MDPT2;

NCIt definition : Human CTNNA1 wild-type allele is located in the vicinity of 5q31 and is approximately 210 kb in length. This allele, which encodes catenin alpha-1 protein, plays a role in the mediation of both protein-protein interactions and cellular adhesion.;

NCIt note : Loss of the CTNNA1 gene is associated with increased tumorigenic properties in vitro.;

GenBank Accession Number : D13866;

PubMed : 20393555;

Details

Origin ID

C88986;

UMLS CUI

C2982438;

OMIM relation
- Catenin, alpha-1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 5q31 [NCIt concept]
gene_is_element_in_pathway
- Adherens Junction Assembly Pathway [NCIt concept]
- Arrhythmogenic Right Ventricular Cardiomyopathy Pathway [NCIt concept]
- Bacterial Invasion of Epithelial Cell Pathway [NCIt concept]
- Cell to Cell Adhesion Signaling Pathway [NCIt concept]
- Endometrial Cancer Pathway [NCIt concept]
- Leukocyte Transendothelial Migration Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Movement Process [NCIt concept]
- Cell-Cell Adhesion Process [NCIt concept]
- Cytoskeletal Process [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Regulation of Cell Shape [NCIt concept]

Keyword's position in hierarchy(ies) :

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