Recombinant Thyroid-Stimulating Hormone

Preferred Label : Recombinant Thyroid-Stimulating Hormone;

NCIt synonyms : Thyroid Stimulating Hormone; Recombinant TSH;

NCIt related terms : THYROTROPIN;

NCIt definition : A recombinant form of the heterodimeric human anterior pituitary glycoprotein thyroid-stimulating hormone (TSH) with potential use in hormone replacement therapy. Recombinant TSH binds to TSH receptors on thyroid epithelial cells and stimulates TSH-dependent signaling pathways. This stimulates iodine uptake and organification, and induces synthesis and secretion of thyroglobulin (Tg), triiodothyronine (T3), and thyroxine (T4).;

UNII : 02KSI6Z9AK;

CAS number : 9002-71-5;

Drug name : Thytropar;

Details

Origin ID

C887;

UMLS CUI

C1535531;

Currated CISMeF NLP mapping
- TSH [MedDRA LLT]
- Thyroid stimulating hormone [MedDRA LLT]
- Thyrotrophin [MedDRA LLT]
- Thyrotrophin (substance) [SNOMED CT concept]
- Thyrotropin [FMA entity]
- Thyrotropin [LOINC component]
- Thyrotropin [MedDRA LLT]
- thyroid stimulating hormone [SNOMED Notion]
- thyrotropin [ATC Code]
- thyrotropin [ATC Code]
- thyrotropin [Substance BNPC]
- thyrotropin [MeSH Descriptor]
- thyrotropin [MeSH concept]
- tsh [TUV Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Hormone [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to BTNT
- thyrotropin alfa [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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