Gantenerumab - CISMeF

Preferred Label : Gantenerumab;

NCIt synonyms : Immunoglobulin G1, anti-(human 1-40-beta-amyloid/human 1-42-beta-amyloid) (human monoclonal gamma-1-chain), disulfide with human monoclonal kappa-chain, dimer;

NCIt definition : A monoclonal antibody against beta-amyloid (Abeta40/42) used in the treatment of Alzheimer's disease. Gantenerumab targets and binds to beta amyloid then is removed through effector cell-mediated clearance. This reduces the level of beta amyloid in the brain. In Alzheimer's disease, beta amyloid accumulates in the brain and is a key component in plaque formation.;

UNII : 4DF060P933;

CAS number : 1043556-46-2;

Molecule name : R-1450; R04909832;

Details

Origin ID

C88580;

UMLS CUI

C2982066;

Currated CISMeF NLP mapping
- gantenerumab [MeSH concept]
- gantenerumab [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- gantenerumab [MeSH Supplementary Concept]
- gantenerumab [MeSH concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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