Ann Arbor Stage IV Mixed Cellularity Classic Hodgkin Lymphoma

Preferred Label : Ann Arbor Stage IV Mixed Cellularity Classic Hodgkin Lymphoma;

NCIt synonyms : Stage IV Mixed Cellularity Hodgkin Lymphoma; Stage IV Mixed Cellularity Hodgkin's Disease; Stage IV Mixed Cellularity Hodgkin's Lymphoma; Mixed Cellularity Hodgkin's Disease Stage IV; Mixed Cellularity Hodgkin's Lymphoma Stage IV; Stage IV Mixed Cellularity Hodgkin s Lymphoma; Stage IV Mixed Cellularity Classical Hodgkin Lymphoma; Ann Arbor Stage IV Mixed Cellularity Classical Hodgkin Lymphoma;

NCIt definition : Ann Arbor Classification: Stage IV: Diffuse or disseminated involvement of one or more extralymphatic organs, with or without associated lymph node involvement; or isolated extralymphatic organ involvement in the absence of adjacent regional lymph node involvement, but in conjunction with disease in distant site(s); or any involvement of the liver or bone marrow, lungs (other than by direct extension from another site), or cerebrospinal fluid.;

Neoplastic status : Malignant;

Details

Origin ID

C8835;

UMLS CUI

C0855081;

Currated CISMeF NLP mapping
- Hodgkin's disease mixed cellularity stage IV [MedDRA Preferred Term]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Plasma Cell [NCIt concept]
Disease may have findings
- CD15-Positive Neoplastic Cells Present [NCIt concept]
- CD30-Positive Neoplastic Cells Present [NCIt concept]
- Colony-Stimulating Factor Overexpression [NCIt concept]
- Fever [NCIt concept]
- Interleukin-10 Overexpression [NCIt concept]
- Interleukin-13 Overexpression [NCIt concept]
- Interleukin-2 Overexpression [NCIt concept]
- Interleukin-5 Overexpression [NCIt concept]
- Interleukin-6 Overexpression [NCIt concept]
- Interleukin-7 Overexpression [NCIt concept]
- Interleukin-9 Overexpression [NCIt concept]
- Lymphadenopathy [NCIt concept]
- Lymphotoxin-Alpha Overexpression [NCIt concept]
- Night Sweats [NCIt concept]
- Transforming Growth Factor-Beta Overexpression [NCIt concept]
- Weight Loss [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Hodgkin's disease mixed cellularity stage IV [MedDRA Preferred Term]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Classic Reed-Sternberg Cell [NCIt concept]
- Hodgkin Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
- Reed-Sternberg Cell [NCIt concept]
disease_has_finding
- Chronic Inflammatory Infiltrate [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Mature Lymphocyte [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
disease_is_stage
- Ann Arbor Stage [NCIt concept]
- Stage IV [NCIt concept]
disease_may_have_abnormal_cell
- Mummified Cell [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 12q [NCIt concept]
- Gain of Chromosome 2p [NCIt concept]
- Gain of Chromosome 9p [NCIt concept]
disease_may_have_molecular_abnormality
- Apoptotic Pathway Deregulation [NCIt concept]
- Clonal Immunoglobulin Heavy Chain Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Kappa Light Chain Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Lambda Light Chain Gene Rearrangement [NCIt concept]
- Clonal T-Cell Receptor Gene Rearrangement [NCIt concept]
disease_may_have_normal_cell_origin
- Mature B-Lymphocyte at the Germinal Center Stage of Differentiation [NCIt concept]
- Peripheral (Post-Thymic) T-Lymphocyte [NCIt concept]

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