Preferred Label : Archexin;
NCIt synonyms : Akt-1 Antisense Oligonucleotide RX-0201;
NCIt definition : A 20-mer antisense oligodeoxynucleotide (ODN) against the proto-oncogene Akt with
potential antineoplastic activity. Akt-1 antisense oligonucleotide RX-0201 binds to
Akt-1 mRNA, inhibiting translation of the transcript; suppression of Akt-1 expression
may result in the inhibition of cellular proliferation and the induction of apoptosis
in tumor cells that overexpress Akt-1. Akt-1 is a serine-threonine protein kinase
that stimulates proliferation and inhibits apoptosis of tumor cells.;
UNII : 4TEW51C830;
Molecule name : RX-0201;
Chemical formula : C194H228N70O103P19S19;
NCI Metathesaurus CUI : CL413599;
Origin ID : C88335;
UMLS CUI : C2981852;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- concept_is_in_subset
