NCIt definition : The hydrochloride salt of ramosetron, a selective serotonin (5-HT) receptor antagonist
with potential antiemetic activity. Upon administration, ramosetron selectively binds
to and blocks the activity of 5-HT subtype 3 (5-HT3) receptors located in the vagus
nerve terminal and in the vomiting center in the central nervous system (CNS), suppressing
chemotherapy-induced nausea and vomiting.;