Preferred Label : Antiperspirant Cream F511;
NCIt related terms : F511 cream;
NCIt definition : A cream formulation containing aluminum chlorohydrate with astringent and antiperspirant
activities. Upon topical application of F511 cream, aluminium chlorohydrate forms
a gel matrix in the sweat gland which subsequently reduces, then stops the flow of
water. In addition, this agent exerts an astringent effect, thereby further preventing
sweat formation. Hyperhidrosis appears to play a role in the development of certain
mucocutaneous reactions, such as palmar-plantar erythrodysesthesia (PPE), upon administration
of chemotherapeutic agents such as doxorubicin, 5-fluorouracil, and capecitabine.;
Alternative definition : NCI-GLOSS: A substance being studied in the prevention of palmar-plantar erythrodysesthesia
(pain, swelling, numbness, tingling, or redness of the palms of the hands or soles
of the feet) in breast cancer patients treated with anticancer drugs. F511 cream contains
a substance that is used in products to control excess sweating under the arms and
on the palms of the hands and soles of the feet. It is a type of antiperspirant.;
NCI Metathesaurus CUI : CL413532;
Codes from synonyms : CDR0000666211;
Origin ID : C88282;
UMLS CUI : C2981805;
Semantic type(s)
- concept_is_in_subset
