Preferred Label : Multikinase Inhibitor SAR103168;
NCIt definition : A multikinase inhibitor with potential antineoplastic activity. Upon intravenous infusion,
multikinase inhibitor SAR103168 may, through the inhibition of multiple kinases, inhibit
the phosphorylation and activation of signal transducer and activator of transcription
5 (STAT5). STAT5, a protein often upregulated in cancer cells, plays a key role in
signal transduction pathways and the suppression of apoptosis.;
Molecule name : SAR103168;
Origin ID : C88278;
UMLS CUI : C2981800;
Semantic type(s)
UMLS correspondences (same concept)
concept_is_in_subset