Preferred Label : Fluorine F 18 ISO-1;
NCIt synonyms : [18F]ISO-1;
NCIt definition : A radioconjugate consisting of the benzamide ligand ISO-1 labeled with the radioisotope
fluorine F18 with positron-emitting radioisotope activity. Upon administration, fluorine
[F18]ISO-1 binds to sigma-2 receptors, located on tumor cells, allowing visualization
of sigma-2 receptor-expressing tumor cells with positron emission tomography (PET).
Sigma-2 receptors, expressed in a variety of normal healthy tissues such as liver,
kidneys, endocrine glands, and in the central nervous system, may be overexpressed
in tumor cells.;
NCI Metathesaurus CUI : CL412443;
Origin ID : C88265;
UMLS CUI : C2981788;
Semantic type(s)
- concept_is_in_subset
