Preferred Label : WT1 mRNA-Electroporated Autologous Dendritic Cell Vaccine;
NCIt synonyms : Wilms Tumor 1 mRNA-Electroporated Autologous Dendritic Cell Vaccine;
NCIt definition : A cancer vaccine containing autologous dendritic cells electroporated with full-length
mRNA encoding Wilms' tumor 1 (WT1) antigen with potential immunostimulatory and antineoplastic
activities. Upon administration, WT1 mRNA-electroporated autologous dendritic cell
vaccine may elicit a cytotoxic T-cell (CTL) response against tumor cells expressing
WT1. Wt1 is frequently overexpressed in a variety of tumor cell types and often correlates
with disease progression and poor prognosis.;
NCI Metathesaurus CUI : CL412436;
Origin ID : C88260;
UMLS CUI : C2981784;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
