Preferred Label : Stage IVA Mycosis Fungoides and Sezary Syndrome AJCC v7;
NCIt synonyms : Stage IVA Mycosis Fungoides and Sézary Syndrome AJCC v7; Stage IVA Mycosis Fungoides and Sézary Syndrome;
NCIt related terms : Stage IVA Mycosis Fungoides and Sezary Syndrome;
NCIt definition : Stage IVA includes: IVA1 (T1-4, N0-2, M0, B2); IVA2 (T1-4, N3, M0, B0-2). T1: Limited
patches, papules, and/or plaques covering less than 10% of the skin surface. May further
stratify into T1a (patch only) vs. T1b (plaque /- patch). T2: Patches, papules, or
plaques covering 10% or more of the skin surface. May further stratify into T2a (patch
only) vs. T2b (plaque /- patch). T3: One or more tumors (equal or greater than 1
cm diameter). T4: Confluence of erythema covering 80% or more of body surface area.
N0: No clinically abnormal peripheral lymph nodes; biopsy not required. N1: Clinically
abnormal peripheral lymph nodes; histopathology Dutch grade 1 or NCI LN0-2. N2: Clinically
abnormal peripheral lymph nodes; histopathology Dutch grade 2 or NCI LN3. N3: Clinically
abnormal peripheral lymph nodes; histopathology Dutch grades 3-4 or NCI LN4; clone
positive or negative. M0: No visceral organ involvement. B0: Absence of significant
blood involvement: 5% or less of peripheral blood lymphocytes are atypical (Sezary
cells). B1: Low blood tumor burden: more than 5% of peripheral blood lymphocytes are
atypical (Sezary cells) but does not meet the criteria of B2. B2: High blood tumor
burden: 1000/microL Sezary cells or more with positive clone. (AJCC 7th ed.);
Neoplastic status : Malignant;
NCI Metathesaurus CUI : CL416017;
Origin ID : C88161;
UMLS CUI : C2981720;
Disease excludes abnormal cell
- Disease excludes normal cell origin
- Has associated anatomic sites
- Semantic type(s)
- concept_is_in_subset
- disease_excludes_finding
- disease_has_abnormal_cell
- disease_has_finding
- disease_has_normal_cell_origin
- disease_has_normal_tissue_origin
- disease_has_primary_anatomic_site
- disease_is_stage
- disease_may_have_molecular_abnormality
