Preferred Label : Clevidipine Butyrate Injectable Emulsion;
NCIt definition : An injectable phospholipid emulsion containing the butyrate salt of the synthetic,
short-acting, dihydropyridine L-type calcium channel antagonist clevidipine with antihypertensive
activity. Clevidipine specifically binds to calcium channels in vascular smooth muscle
cells, inhibiting the influx of extracellular calcium ions into vascular smooth muscle
cells. This results in dilatation of systemic arteries, a decrease in systemic vascular
resistance and so a decrease in arterial blood pressure. This agent is metabolized
by esterases in the blood and extravascular tissues to an inactive carboxylic acid
metabolite.;
Drug name : Cleviprex;
Origin ID : C88036;
UMLS CUI : C2981617;
Semantic type(s)
- concept_is_in_subset
