Fontolizumab - CISMeF

Preferred Label : Fontolizumab;

NCIt synonyms : Immunoglobulin G1, Anti-(Human Interferon Gamma) (Human-Mouse Monoclonal Huzaf Gamma-1-Chain), Disulfide with Human-Mouse Monoclonal Huzaf Light Chain, Dimer;

NCIt definition : A humanized monoclonal antibody directed against interferon-gamma (IFN-g) with immunomodulatory activity. Fontolizumab binds to and prevents the activity of IFN-g. This leads to a suppression of IFN-g-mediated signaling and thus a suppression of IFN-g immune related responses. IFN-g is a cytokine often overexpressed in various auto-immune diseases.;

UNII : 6J92H2439Z;

CAS number : 326859-36-3;

Molecule name : HUZAF;

Details

Origin ID

C87765;

UMLS CUI

C1682646;

Currated CISMeF NLP mapping
- fontolizumab [MeSH concept]
- fontolizumab [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- fontolizumab [MeSH concept]
- fontolizumab [MeSH Supplementary Concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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