NCIt synonyms : Immunoglobulin G1, Anti-(Human/Macaca irus/Rattus/Mus musculus Interleukin 22) (Human
Monoclonal Heavy Chain), Disulfide with Human Monoclonal Lambda-Chain, Dimer; Immunoglobulin G1, Anti-(Human Interleukin 22) (Human Monoclonal Heavy Chain), Disulfide
with Human Monoclonal Lambda-Chain, Dimer;
NCIt definition : A human monoclonal antibody directed against interleukin-22 (IL-22) with anti-inflammatory
activity. Fezakinumab binds to IL-22 and prevents the activity of this interleukin.
This leads to an inhibition of inflammation. IL-22, a cytokine and member of the IL-10
superfamily, plays a key role during inflammatory responses.;