Efungumab - CISMeF

Preferred Label : Efungumab;

NCIt synonyms : Immunoglobulin, Anti-(Candida Heat-Shock Protein Hsp 90) (Human Monoclonal Hsp90mab Fragment);

NCIt definition : A human single-chain variable fragment of a monoclonal antibody against fungal Hsp90 with anti-fungal activity. Efungumab binds to heat shock protein 90 (Hsp90) located on the fungal cell surface, thereby preventing cell wall synthesis and repair. This decreases the integrity of the fungal cell wall and prevents further fungal cell growth. In addition, as Hsp90 is a molecular chaperone, inhibition of its function may increase the cytotoxic effect of other antifungal agents.;

UNII : BM86P708HW;

CAS number : 762260-74-2;

Drug name : Mycograb;

Molecule name : MYC123B; MYC124; MYC123A; MYC123;

Détails

Origin ID

C87763;

UMLS CUI

C2605768;

Currated CISMeF NLP mapping
- efungumab [MeSH concept]
- efungumab [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- efungumab [MeSH concept]
- efungumab [MeSH Supplementary Concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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