NCIt related terms : FERUMOXYTOL NON-STOICHIOMETRIC MAGNETITE;
NCIt definition : A superparamagnetic iron oxide nanoparticle coated with a low molecular weight semi-synthetic
carbohydrate, polyglucose sorbitol carboxymethyl ether, with potential anti-anemic
and imaging properties. After intravenous administration, ferumoxytol replaces iron
stores with fewer side effects compared to the use of oral iron. In addition, this
agent generates T1 relaxation, producing a magnetic field and enhancing T2 relaxation,
thereby darkening contrast media-containing structures in magnetic resonance imaging
(MRI). Due to small particle size, ferumoxytol remains in the intravasculature for
a prolonged period and so may be used as a blood pool agent.;
Alternative definition : NCI-GLOSS: A nanoparticle form of iron made in the laboratory that is being studied
for use in iron replacement therapy, and as a contrast agent for magnetic resonance
imaging. Contrast agents are substances that are injected into the body and taken
up by certain tissues, making the tissues easier to see in imaging scans.;