Preferred Label : Sulopenem Etzadroxil;
NCIt synonyms : 4-Thia-1-Azabicyclo(3.2.0)Hept-2-Ene-2-Carboxylic Acid, 6-((1R)-1-Hydroxyethyl)-7-Oxo-3-(((1R,3S)-Tetrahydro-1-Oxido-3-Thienyl)Thio)-,
(2-Ethyl-1-Oxobutoxy)Methyl Ester, (5R,6S)-; Methylene 2-Ethylbutanoate (5R,6S)-6-((1R)-1-Hydroxyethyl)-7-Oxo-3-(((1R,3S)-1-Oxotetrahydro-1H-1-lambda(Sup
4)-Thiophen-3-yl)Sulfanyl)-4-Thia-1-Azabicyclo(3.2.0)Hept-2-Ene-2-Carboxylate;
NCIt definition : An orally available ester prodrug form of sulopenem, a thiopenem with broad-spectrum
antibacterial activity against most gram-positive and gram-negative bacteria. After
oral administration of sulopenem etzadroxil, the ester bond is cleaved, releasing
active sulopenem. Sulopenem is not active against Pseudomonas aeruginosa. In addition,
this agent is fairly stable against hydrolysis by various beta-lactamases.;
UNII : 492M3I304T;
InChIKey : NBPVNGWRLGHULH-CSOWVJSESA-N;
CAS number : 1000296-70-7;
Molecule name : PF-03709270;
Chemical formula : C19H27NO7S3;
Origin ID : C87678;
UMLS CUI : C2981328;
Currated CISMeF NLP mapping
- Semantic type(s)
- concept_is_in_subset
