N-Acetylcysteine Amide

Preferred Label : N-Acetylcysteine Amide;

NCIt synonyms : NACA; N-Acetylcysteinamide; N-Acetyl-Cysteine-Amide; N-Acetyl-L-Cysteine Amide; NAC Amide; N-Acetyl Cysteine Amide;

NCIt related terms : ACETYLCYSTEINAMIDE;

CISMeF acronym : NACA;

NCIt definition : The amide form of N-acetylcysteine (NAC), a synthetic N-acetyl derivative and prodrug of the endogenous amino acid and antioxidant glutathione (GSH) precursor L-cysteine, with potential antioxidant and anti-inflammatory activities. Upon administration, N-acetylcysteine amide (NACA) increases GSH levels. GSH scavenges reactive oxygen species (ROS), reduces oxidative stress and prevents ROS-mediated cell damage and apoptosis. NACA has enhanced lipophilicity and membrane permeability compared with NAC.;

UNII : 4N69717RKW;

InChIKey : UJCHIZDEQZMODR-BYPYZUCNSA-N;

CAS number : 38520-57-9;

Molecule name : AD4;

Chemical formula : C5H10N2O2S;

Details

Origin ID

C87651;

UMLS CUI

C1452654;

Automatic exact mappings (from CISMeF team)
- Nascent polypeptide-associated complex, alpha polypeptide [OMIM gene]
- nascent polypeptide-associated complex [GO term]
Currated CISMeF NLP mapping
- N-Acetylcysteinamide [MeSH concept]
- N-Acetylcysteinamide [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- N-Acetylcysteinamide [MeSH concept]
- N-Acetylcysteinamide [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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