Preferred Label : Demecarium;
NCIt synonyms : Benzenaminium, 3,3'-(1,10-Decanediylbis((Methylimino)Carbonyloxy))Bis(N,N,N-Trimethyl)-; 3,3'-(1,10-Decanediylbis((Methylimino)Carbonyloxy))Bis(N,N,N-Trimethylbenzenaminium); (M-Hydroxyphenyl)Trimethylammonium Decamethylenebis(Methylcarbamate); N,N'-Bis(3-Trimethylammoniumphenoxycarbonyl)-N,N'-Dimethyldecamethylenediamine;
NCIt definition : A quaternary ammonium compound that serves as a long-acting cholinesterase inhibitor
with parasympathomimetic activity. When used topically, demecarium inactivates both
pseudocholinesterase and acetylcholinesterase, thereby preventing acetylcholine breakdown
and increasing acetylcholine activity. This causes contraction of the iris sphincter
muscle (producing miosis) and the ciliary muscle (affecting the accommodation reflex).
In so doing, this agent increases the outflow of the aqueous humor, thereby reducing
intraocular pressure.;
UNII : ILP8XJ8R5K;
InChIKey : RWZVPVOZTJJMNU-UHFFFAOYSA-N;
CAS number : 16505-84-3;
Chemical formula : C32H52N4O4;
Origin ID : C87481;
UMLS CUI : C0360174;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- concept_is_in_subset
