Pseudoisocytidine

Preferred Label : Pseudoisocytidine;

NCIt synonyms : 5-(Beta-D-Ribofuranosyl)Isocytosine; 4(1H)-Pyrimidinone, 2-Amino-5-Beta-D-Ribofuranosyl-; psi Icyd;

NCIt definition : A synthetic, pyrimidine C-5 nucleoside with antineoplastic activity. Pseudoisocytidine, after conversion into pseudoisocytidine triphosphate, is incorporated into DNA and RNA eventually halting tumor cell proliferation. Compared to 5-azacytidine and cytarabine, this agent shows enhanced stability and resistance to enzymatic deamination.;

UNII : TDH73L8XQD;

InChIKey : MPDKOGQMQLSNOF-GBNDHIKLSA-N;

CAS number : 57100-18-2;

Chemical formula : C9H13N3O5;

Details

Origin ID

C87389;

UMLS CUI

C0072540;

Automatic exact mappings (from CISMeF team)
- psi-cytidine [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- pseudoisocytidine [MeSH concept]
- pseudoisocytidine [MeSH Supplementary Concept]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- pseudoisocytidine [MeSH concept]
- pseudoisocytidine [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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