Soraprazan - CISMeF

Preferred Label : Soraprazan;

NCIt synonyms : (7R,8R,9R)-7-(2-Methoxyethoxy)-2,3-Dimethyl-9-Phenyl-7,8,9,10-Tetrahydroimidazo(1,2-H)(1,7)Naphtyridin-8-ol;

NCIt definition : A potent and reversible inhibitor of the gastric H /K ATPase proton pump with potassium-competitive acid blocking (P-CAB) activity. Soraprazan binds very specifically, competitively and reversibly to the potassium binding site of the proton pump hydrogen-potassium adenosine triphosphatase (H /K ATPase), thereby inhibiting the pump's activity and the parietal cell secretion of H ions into the gastric lumen, the final step in gastric acid production.;

UNII : 5XB3671655;

InChIKey : PWILYDZRJORZDR-MISYRCLQSA-N;

CAS number : 261944-46-1;

Chemical formula : C21H25N3O3;

Details

Origin ID

C87388;

UMLS CUI

C1958611;

Automatic exact mappings (from CISMeF team)
- 2,3-dimethyl-8-hydroxy-7-(2-methoxyethoxy)-9-phenyl-7,8,9,10-tetrahydroimidazo(1,2-h)(1,7)naphthyridine [MeSH concept]
- soraprazan [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- soraprazan [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- soraprazan [MeSH Supplementary Concept]
- soraprazan [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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