Sodium Selenite

Preferred Label : Sodium Selenite;

NCIt synonyms : Selenious Acid Disodium Salt; Selenious Acid, Sodium Salt (1:2); Disodium Selenium Trioxide;

NCIt definition : An inorganic form of the trace element selenium with potential antineoplastic activity. Selenium, administered in the form of sodium selenite, is reduced to hydrogen selenide (H2Se) in the presence of glutathione (GSH) and subsequently generates superoxide radicals upon reaction with oxygen. This may inhibit the expression and activity of the transcription factor Sp1; in turn Sp1 down-regulates androgen receptor (AR) expression and blocks AR signaling. Eventually, selenium may induce apoptosis in prostate cancer cells and inhibit tumor cell proliferation.;

UNII : HIW548RQ3W;

InChIKey : BVTBRVFYZUCAKH-UHFFFAOYSA-L;

CAS number : 10102-18-8; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 10102-18-8 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : 2Na.O3Se;

ChEBI ID : CHEBI:48843;

Details

Origin ID

C87346;

UMLS CUI

C0142923;

Automatic exact mappings (from CISMeF team)
- Sodium selenite [ICD-11 Extension code]
Semantic type(s)
- Inorganic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Sodium selenite (substance) [SNOMED CT concept]
- pentahydrate of Sodium Selenite [International Nonproprietary Name]
- sodium selenite [ATC Code]
- sodium selenite [Substance BNPC]
- sodium selenite [MeSH concept]
- sodium selenite [MeSH Descriptor]
- sodium selenite [SNOMED Notion]
Validated automatic mappings to BTNT
- sodium selenite [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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