Brotizolam - CISMeF

Preferred Label : Brotizolam;

NCIt synonyms : 2-Bromo-4-(O-Chlorophenyl)-9-Methyl-6H-Thieno(3,2-F)-S-Triazolo(4,3-A)(1,4)Diazepine; 6H-Thieno(3,2-F)(1,2,4)Triazolo(4,3-A)(1,4)Diazepine,2-Bromo-4-(2-Chlorophenyl)-9-Methyl-;

NCIt definition : A triazolo-benzodiazepine derivative with sedative, hypnotic, anxiolytic and anticonvulsant activities. Brotizolam binds to the benzodiazepine binding site on the gamma aminobutyric acid (GABA)-A receptor in the central nervous system (CNS). This leads to an increase in the opening of chloride channels, membrane hyperpolarization and increases the inhibitory effect of GABA on the CNS.;

UNII : 5XZM1R3DKF;

InChIKey : UMSGKTJDUHERQW-UHFFFAOYSA-N;

CAS number : 57801-81-7;

Molecule name : WE-941;

Chemical formula : C15H10BrClN4S;

Details

Origin ID

C87057;

UMLS CUI

C0054151;

Automatic exact mappings (from CISMeF team)
- Brotizolam [ICHI extension code]
CISMeF manual mappings
- Brotizolam (substance) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Brotizolam [ICD-11 Extension code]
- Brotizolam (substance) [SNOMED CT concept]
- brotizolam [ATC Code]
- brotizolam [Substance BNPC]
- brotizolam [MeSH concept]
- brotizolam [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- brotizolam [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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