T Lymphoblastic Leukemia/Lymphoma

Preferred Label : T Lymphoblastic Leukemia/Lymphoma;

NCIt synonyms : Precursor T Lymphoblastic Leukemia/Lymphoma; Precursor T Lymphoblastic Lymphoma/Leukemia; Precursor T-Lymphoblastic Lymphoma/Leukemia; Precursor T Lymphoblastic Leukemia Lymphoma; T-Lymphoblastic Leukemia/Lymphoma; T-Cell Lymphoblastic Leukemia/Lymphoma;

NCIt definition : A neoplasm of lymphoblasts committed to the T-cell lineage, typically composed of small to medium-sized blast cells. When the neoplasm involves predominantly the bone marrow and the peripheral blood, it is called T acute lymphoblastic leukemia. When it involves nodal or extranodal sites it is called T lymphoblastic lymphoma. (WHO, 2001);

Neoplastic status : Malignant;

ICD-O code : 9837/3;

Details

Origin ID

C8694;

UMLS CUI

C1301359;

Automatic exact mappings (from CISMeF team)
- Precursor T cell lymphoblastic leukemia/lymphoblastic lymphoma (morphologic abnormality) [SNOMED CT concept]
- T lymphoblastic leukemia/lymphoma (morphologic abnormality) [SNOMED CT concept]
- T-cell acute lymphoblastic leukemia [DO Concept]
- T-cell lymphoblastic leukemia/lymphoma [DO Concept]
- precursor T-lymphoblastic lymphoma/leukemia [DO Concept]
CISMeF manual mappings
- Precursor T cell lymphoblastic leukemia/lymphoblastic lymphoma (disorder) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Precursor T-lymphoblastic lymphoma/leukaemia [MedDRA Preferred Term]
- Precursor T-lymphoblastic lymphoma/leukaemia NOS [MedDRA LLT]
- Precursor T-lymphoblastic lymphoma/leukemia [MedDRA LLT]
- Precursor T-lymphoblastic lymphoma/leukemia NOS [MedDRA LLT]
- Precursor T-lymphoblastic lymphomas/leukaemias [MedDRA High Level Term]
- precursor T-Cell lymphoblastic Leukemia-Lymphoma [MeSH concept]
- precursor t-cell lymphoblastic leukemia-lymphoma [MeSH Descriptor]
Disease excludes abnormal cell
- Neoplastic B-Lymphocyte [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Peripheral (Post-Thymic) T-Lymphocyte [NCIt concept]
Disease may have findings
- Hepatomegaly [NCIt concept]
- Lymphadenopathy [NCIt concept]
- Malignant Pleural Effusion [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Precursor T cell lymphoblastic leukemia/lymphoblastic lymphoma (disorder) [SNOMED CT concept]
- Precursor T cell lymphoblastic leukemia/lymphoblastic lymphoma (morphologic abnormality) [SNOMED CT concept]
- Precursor T-lymphoblastic lymphoma/leukaemia [MedDRA Preferred Term]
- Precursor T-lymphoblastic lymphoma/leukaemia NOS [MedDRA LLT]
- Precursor T-lymphoblastic lymphoma/leukemia [MedDRA LLT]
- Precursor T-lymphoblastic lymphoma/leukemia NOS [MedDRA LLT]
- Precursor T-lymphoblastic lymphomas/leukaemias [MedDRA High Level Term]
- T lymphoblastic leukemia/lymphoma (morphologic abnormality) [SNOMED CT concept]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphoblast [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
- Neoplastic T-Lymphoblast [NCIt concept]
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
disease_has_associated_gene
- TAL2 Gene [NCIt concept]
- TAL2 wt Allele [NCIt concept]
disease_has_finding
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphoblast [NCIt concept]
- Lymphocyte [NCIt concept]
- Precursor T-Lymphoblast [NCIt concept]
- T-Lymphocyte and Natural Killer Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
disease_mapped_to_gene
- NOTCH1 Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- del(9p21p22) [NCIt concept]
- inv(14)(q11;q32.1) [NCIt concept]
- t(10;14)(q24;q11) [NCIt concept]
- t(11;14)(p13;q11) [NCIt concept]
- t(11;14)(p15;q11) [NCIt concept]
- t(14;14)(q11;q32) [NCIt concept]
- t(1;14)(p32;q11) [NCIt concept]
- t(1;7)(p33;q35) [NCIt concept]
- t(7;10)(q34;q24) [NCIt concept]
- t(7;14)(q35;q32.1) [NCIt concept]
- t(7;19)(q34;q13) [NCIt concept]
- t(7;9)(q34;q32) [NCIt concept]
- t(7;9)(q34;q34.3) [NCIt concept]
- t(8;13)(p11;q11) [NCIt concept]
disease_may_have_molecular_abnormality
- Clonal T-Cell Receptor Beta Chain Gene Rearrangement [NCIt concept]
- Clonal T-Cell Receptor Gamma Chain Gene Rearrangement [NCIt concept]
- NOTCH1 Gene Mutation [NCIt concept]
human_disease_maps_to_eo_disease
- Mouse Precursor T Cell Lymphoblastic Lymphoma/Leukemia [NCIt concept]
pathogenesis_of_disease_involves_gene
- NOTCH1 Gene [NCIt concept]
- NOTCH1 wt Allele [NCIt concept]

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