Stage IV Chronic Lymphocytic Leukemia

Preferred Label : Stage IV Chronic Lymphocytic Leukemia;

NCIt synonyms : CLL Stage IV; Chronic Lymphocytic Leukemia Stage IV; Stage IV Chronic Lymphocytic Leukemia- Modified Rai Staging System; Stage IV CLL;

NCIt related terms : Stage IV Chronic Lymphocytic Leukemia (CLL);

NCIt definition : Risk: High; Findings: Lymphocytosis and platelets less than 100,000/microliter; Survival (months): 30. (from AJCC 8th Ed.);

Alternative definition : NCI-GLOSS: There are too many lymphocytes in the blood and too few platelets. The lymph nodes, liver, or spleen may be larger than normal and there may be too few red blood cells.;

Neoplastic status : Malignant;

Codes from synonyms : CDR0000045062;

Details

Origin ID

C8646;

UMLS CUI

C0854804;

Disease excludes abnormal cell
- Leukemic Plasma Cell [NCIt concept]
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Precursor B-Lymphoblast [NCIt concept]
Disease may have findings
- Fatigue [NCIt concept]
- Lymphadenopathy [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Chronic lymphocytic leukaemia stage 4 [MedDRA Preferred Term]
- Chronic lymphocytic leukaemia stage C(IV) [MedDRA LLT]
- Chronic lymphocytic leukemia stage 4 [MedDRA LLT]
- Chronic lymphocytic leukemia stage C(IV) [MedDRA LLT]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
disease_excludes_finding
- Acute Clinical Course [NCIt concept]
- Benign Cellular Infiltrate [NCIt concept]
- Solid Growth Pattern [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Leukemic Cell [NCIt concept]
- Leukemic Lymphocyte [NCIt concept]
- Leukemic Small Lymphocyte with Clumped Chromatin [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic B-Lymphocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
- Neoplastic Small Lymphocyte with Clumped Chromatin [NCIt concept]
disease_has_finding
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_molecular_abnormality
- Clonal Immunoglobulin Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Heavy Chain Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Kappa Light Chain Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Lambda Light Chain Gene Rearrangement [NCIt concept]
disease_has_normal_cell_origin
- B-Lymphocyte [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Mature B-Lymphocyte [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
disease_is_stage
- Rai Stage [NCIt concept]
- Stage IV [NCIt concept]
disease_mapped_to_chromosome
- Human Chromosome 11 [NCIt concept]
- Human Chromosome 12 [NCIt concept]
- Human Chromosome 13 [NCIt concept]
- Human Chromosome 17 [NCIt concept]
- Human Chromosome 6 [NCIt concept]
disease_mapped_to_gene
- BCL3 Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 12q13 [NCIt concept]
- Trisomy 12 [NCIt concept]
- del(11q22q23) [NCIt concept]
- del(13q14) [NCIt concept]
- del(17p13) [NCIt concept]
- del(6q21) [NCIt concept]
pathogenesis_of_disease_involves_gene
- BCL3 Gene [NCIt concept]
- BCL3 wt Allele [NCIt concept]

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