Preferred Label : Corynebacterium diphtheriae;
NCIt definition : A species of aerobic or facultatively anaerobic, Gram-positive, coryneform, pleomorphic
bacilli assigned to the phylum Actinobacteria. This species is nonmotile, non-spore
forming, catalase positive, non-lipophilic, produces diphtheria toxin which inhibits
elongation factor 2 (EF-2) thus preventing protein synthesis, forms polar granules,
and is cultured in Loeffler's serum in a low iron environment or on tellurite agar.
C diphtheriae is commensal in the skin and nasopharynx, but toxin producing strains
are pathogenic to humans causing diphtheria; both an antitoxin and vaccine are available
for disease prevention.;
Alternative definition : CDISC: Any bacterial organism that can be assigned to the species Corynebacterium
diphtheriae.;
UNII : 3U7E3O07S8;
Taxon ID : 1717;
Origin ID : C86312;
UMLS CUI : C0010150;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
