Preferred Label : Technetium Tc-99m Sulfur Colloid;
NCIt synonyms : Tc 99m Sulfur Colloid; Technetium Tc 99m Sulfur Colloid;
NCIt related terms : Tc-99m SC;
NCIt definition : A gamma-emitting colloid used in scintillation scanning of the reticuloendothelial
system (RES). After intravenous administration, technetium Tc 99m sulfur colloid is
phagocytized by the reticuloendothelial system and concentrated in the liver, spleen,
and bone marrow; detection/localization of phagocytized gamma ray-emitting colloid
is performed with a gamma-ray scintillation camera. Scintillation scanning using technetium
Tc 99m colloid sulfur helps determine the distribution and function of the RES and
the extent to which tumor involves the RES. The RES includes cells types that can
phagocytize and sequester inert particles and vital dyes; RES cell types include macrophages
or macrophage precursors, specialized endothelial cells lining the sinusoids of the
liver, spleen, and bone marrow, and reticular cells of lymphatic tissue and of bone
marrow.;
Alternative definition : NCI-GLOSS: A substance being studied as a way to find cancer in the body. It is also
used to find sentinel lymph nodes in breast cancer. It contains a radioactive substance
called technetium linked to a substance called sulfur colloid. Sulfer colloid is taken
up by special cells in lymph tissue, and in the liver, spleen, and bone marrow after
it is injected. A machine or probe that detects radioactivity is used to find where
the technetium Tc 99m sulfur colloid is in the body. It is a type of radiopharmaceutical
and a type of radioimaging agent.;
UNII : 556Q0P6PB1;
InChIKey : FJTPHHNWVXNMEK-IEOVAKBOSA-N;
CAS number : 7704-34-9;
Chemical formula : S8.Tc;
Codes from synonyms : CDR0000674717; CDR0000045558; CDR0000674716;
Origin ID : C856;
UMLS CUI : C0039419;
Automatic exact mappings (from CISMeF team)
- CISMeF manual mappings
- Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- concept_is_in_subset
- is_component_of_chemotherapy_regimen
