Preferred Label : Multi-epitope TARP-pulsed Autologous Dendritic Cell Vaccine;
NCIt synonyms : Multi-epitope TARP Peptide-pulsed Autologous Dendritic Cell Vaccine; Autologous TARP Peptide-pulsed Dendritic Cell Vaccine; Multi-epitope TARP-pulsed Autologous DC Vaccine; ME T-cell Receptor Gamma Alternate Reading Frame Protein Peptide-pulsed Autologous
DC Vaccine;
NCIt definition : A cell-based cancer vaccine comprised of autologous dendritic cells pulsed with multiple
antigenic peptides derived from T-cell receptor gamma-chain alternate reading frame
protein (TARP), with potential immunostimulatory and antineoplastic activities. Upon
intradermal administration, multi-epitope (ME) TARP-pulsed autologous dendritic cell
vaccine may stimulate anti-tumor cytotoxic T-lymphocyte (CTL) and antibody responses
against TARP-expressing cancer cells, resulting in tumor cell lysis. The highly immunogenic
nuclear protein TARP is expressed in a variety of cancer cell types.;
NCI Metathesaurus CUI : CL412347;
Origin ID : C85470;
UMLS CUI : C2827692;
Semantic type(s)
- concept_is_in_subset
