Preferred Label : Formoterol Fumarate Oral;
NCIt definition : The orally bioavailable fumarate salt of formoterol, a long-acting, selective beta2-adrenergic
receptor agonist with bronchodilating and potential anti-cachexia and anabolic activities.
In addition to formoterol's bronchodilating activity, formoterol exhibits anti-cachexia
activity through the inhibition of the ATP-ubiquitin-dependent proteolytic system,
which may result in a decrease in protein degradation and muscle cell apoptosis. In
addition, formoterol may also increase insulin-like growth factor (IGF) signaling,
resulting in an increase in protein synthesis. This agent may also inhibit the calcium-dependent
calpain system, resulting in the inhibition of muscle wasting.;
Molecule name : APD209;
NCI Metathesaurus CUI : CL412344;
Origin ID : C85467;
UMLS CUI : C2827690;
Semantic type(s)
- concept_is_in_subset
