Preferred Label : TARP 29-37-9V Peptide Vaccine;
NCIt definition : A peptide-based cancer vaccine, consisting of amino acid residues 29 through 37 of
T cell receptor gamma alternate reading frame protein (TARP) with a leucine-to-valine
substitution at position 9, with potential immunostimulatory and antineoplastic activities.
Upon administration, TARP 29-37-9V peptide vaccine may induce a cytotoxic T-lymphocyte
(CTL) response against TARP-expressing tumor cells, which may result in decreased
tumor cell proliferation. The leucine-to-valine substitution at position 9 of this
peptide improves its immunogenicity. The nuclear protein TARP is commonly expressed
on prostate and breast cancer cells and is highly immunogenic.;
NCI Metathesaurus CUI : CL412335;
Origin ID : C85463;
UMLS CUI : C2827686;
Semantic type(s)
- chemical_or_drug_has_mechanism_of_action
- concept_is_in_subset
