Preferred Label : Fluorine F 18-VM4-037;
NCIt synonyms : [F18]VM4-037;
NCIt definition : A radiopharmaceutical consisting of a sulfonamide covalently attached to the positron-emitting
isotope fluorine F 18 with CA-IX-binding and radioisotopic activities. Upon administration,
the sulfonamide moiety of [F18]VM4-037 binds to the cell-surface tumor-associated
antigen (TAA) carbonic anhydrase IX isoenzyme (CA-IX); CA-IX-expressing tumor cells
can then be visualized using positron emission tomography (PET). CA-IX has been found
to be elevated in a variety of hypoxic tumors; elevated CA-IX has been positively
correlated with tumor growth, tumor invasion and poor prognosis.;
NCI Metathesaurus CUI : CL412318;
Origin ID : C85449;
UMLS CUI : C2827672;
Semantic type(s)
- concept_is_in_subset
- has_target
