Preferred Label : Stage IV Hypopharyngeal Carcinoma AJCC v6;
NCIt synonyms : Stage IV Hypopharynx Carcinoma AJCC v6; Stage IV Carcinoma of Hypopharynx AJCC v6; Stage IV Carcinoma of the Hypopharynx AJCC v6; Stage IV Hypopharyngeal Carcinoma;
NCIt related terms : stage IV hypopharynx cancer; Stage IV Hypopharyngeal Throat Cancer;
NCIt definition : Stage IV includes: IVA (T4a, N0, M0); (T4a, N1, M0); (T1, N2, M0); (T2, N2, M0); (T3,
N2, M0); (T4a, N2, M0); IVB (T4b, Any N, M0); (Any T, N3, M0); IVC (Any T, Any N,
M1). T4a: Tumor invades thyroid/cricoid cartilage, hyoid bone, thyroid gland, esophagus,
or central compartment soft tissue. T4b: Tumor invades prevertebral fascia, encases
carotid artery, or involves mediastinal structures. N2: Metastasis in a single ipsilateral
lymph node, more than 3cm but not more than 6cm in greatest dimension, or in bilateral
or contralateral lymph nodes, none more than 6 cm in greatest dimension. N2a: Metastasis
in a single ipsilateral lymph node more than 3 cm but not more than 6 cm in greatest
dimension. N2b: Metastasis in multiple ipsilateral lymph nodes, none more than 6 cm
in greatest dimension. N2c: Metastasis in bilateral or contralateral lymph nodes,
none more than 6 cm in greatest dimension. N3: Metastasis in a lymph node more than
6 cm in greatest dimension. M1: Distant metastasis. (AJCC 6th ed.);
Alternative definition : NCI-GLOSS: Stage IV hypopharyngeal cancer is divided into stages IVA, IVB, and IVC.
In stage IVA, the tumor is (1) any size and has spread to nearby soft tissue, connective
tissue, the thyroid, or the esophagus; cancer may be found either in one lymph node
on the same side of the neck (the lymph node is 3 centimeters or smaller) or in one
or more lymph nodes anywhere in the neck (all of these lymph nodes are 6 centimeters
or smaller); or (2) in only one area of the hypopharynx, is 2 centimeters or smaller,
and has also spread to one or more lymph nodes anywhere in the neck (all of these
lymph nodes are 6 centimeters or smaller); or (3) in more than one area of the hypopharynx,
is in nearby tissues, or is larger than 2 centimeters but not larger than 4 centimeters
and has not spread to the larynx; cancer has spread to one or more lymph nodes anywhere
in the neck (all of these lymph nodes are 6 centimeters or smaller); or (4) larger
than 4 centimeters or has spread to the larynx; cancer has also spread to one or more
lymph nodes anywhere in the neck (all of these lymph nodes are 6 centimeters or smaller).
In stage IVB, the tumor either (1) has spread to nearby soft tissue, connective tissue,
blood vessels, the thyroid, or the esophagus, and may have spread to lymph nodes of
any size; or (2) is any size and has spread to lymph nodes that are larger than 6
centimeters. In stage IVC, cancer has spread beyond the hypopharynx to other parts
of the body.;
Neoplastic status : Malignant;
Codes from synonyms : CDR0000046102;
Origin ID : C8533;
UMLS CUI : C1336419;
Disease excludes abnormal cell
- Has associated anatomic sites
- Semantic type(s)
- concept_is_in_subset
- disease_excludes_finding
- disease_has_abnormal_cell
- disease_has_finding
- disease_has_normal_cell_origin
- disease_has_normal_tissue_origin
- disease_has_primary_anatomic_site
- disease_is_stage
