Preferred Label : Dapatifagene Navolactibac;
NCIt synonyms : hTFF1-Secreting Lactococcus lactis AG013; Lactococcus Lactis subsp. Cremoris sagx0085; Human Trefoil Factor 1-Secreting Lactococcus lactis AG013;
NCIt definition : An oral rinse solution containing a strain of the bacteria Lactococcus lactis (L.
lactis) genetically modified to express human Trefoil Factor 1 (hTFF1) with potential
cytoprotective activity. With oral rinsing, dapatifagene navolactibac may secrete
and deliver hTFF1 to oral mucosal tissue, protecting or promoting the healing of damaged
oral mucosa. hTFF1, a peptide belonging to the Trefoil factors family (TFF), is normally
secreted by mucous epithelia and is involved in protecting mucosal tissue and maintaining
mucosal surface integrity.;
UNII : 8FFT787E61;
Molecule name : AG013; AG 013;
NCI Metathesaurus CUI : CL412393;
Origin ID : C84842;
UMLS CUI : C5421246;
Semantic type(s)
concept_is_in_subset